Autoantibodies to a 140-kd polypeptide, CADM-140, in Japanese patients with clinically amyopathic dermatomyositis
نویسندگان
چکیده
منابع مشابه
Myositis autoantibodies in Korean patients with inflammatory myositis: Anti-140-kDa polypeptide antibody is primarily associated with rapidly progressive interstitial lung disease independent of clinically amyopathic dermatomyositis
BACKGROUND To investigate the association between myositis autoantibodies and clinical subsets of inflammatory myositis in Korean patients. METHODS Immunoprecipitation was performed using the sera of classic polymyositis (PM) (n = 11) and dermatomyositis (DM) (n = 38) patients who met the Bohan and Peter criteria for definite inflammatory myositis. A panel of defined myositis autoantibodies w...
متن کاملAutoantibodies to a 140-kd protein in juvenile dermatomyositis are associated with calcinosis
OBJECTIVE The identification of novel autoantibodies in juvenile dermatomyositis (DM) may have etiologic and clinical implications. The aim of this study was to describe autoantibodies to a 140-kd protein in children recruited to the Juvenile DM National Registry and Repository for UK and Ireland. METHODS Clinical data and sera were collected from children with juvenile myositis. Sera that re...
متن کاملAnti-CADM-140/MDA5 antibody and clinical subsets of dermatomyositis
The clinical features of dermatomyositis (DM) have a close relationship with myositis-specific antibodies. Clinically amyopathic dermatomyositis (CADM) is a subgroup of DM, which manifests as characteristic skin symptoms compatible with DM, such as Gottron's sign and heliotrope rash with no or mild muscle symptoms. Sometimes, a life-threatening rapidly progressing interstitial lung disease can ...
متن کاملAuthor's response to reviews Title: Myositis autoantibodies in Korean patients with inflammatory myositis: Anti-140-kDa polypeptide antibody is primarily associated with rapidly progressive interstitial lung disease independent of clinically amyopathic dermatomyositis. Authors:
Title: Myositis autoantibodies in Korean patients with inflammatory myositis: Anti-140-kDa polypeptide antibody is primarily associated with rapidly progressive interstitial lung disease independent of clinically amyopathic dermatomyositis.
متن کاملHow Often are Pediatric Patients with Clinically Amyopathic Dermatomyositis Truly Amyopathic?
BACKGROUND Pediatric patients can present with skin manifestations of dermatomyositis without overt weakness (clinically amyopathic juvenile dermatomyositis [JDM]), but it is unclear how often this happens and how often they have subclinical muscle inflammation. OBJECTIVE Our goal was to determine the frequency of clinically amyopathic JDM and the frequency with which a thorough evaluation un...
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ژورنال
عنوان ژورنال: Arthritis & Rheumatism
سال: 2005
ISSN: 0004-3591,1529-0131
DOI: 10.1002/art.21023